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Common low-calorie sweeteners include: aspartame, sucralose, erythritol and other substances. D-aloxulose belongs to the hexose and ketolose groups, which are soft and delicate in taste and close to sucrose but have almost zero calories.
In 2011, aloxulose was approved by the United States as GRAS (United States Additive Safety Indicator Substance); On April 17, 2019, the U.S. Food and Drug Administration (FDA) issued draft guidance on the declaration of aloxone on nutrition labels, agreeing that 0.4 calories per gram of aloxone should be counted, which indicates that aloxone can be used as "0 sugar" in foods.
After the United States FDA certified the safety of aloxone, allowing aloxone as part of the general safety food and dietary supplement food ingredients, New Zealand, South Korea, Canada and other countries have also included aloxone in the food raw materials requirements.
At present, there is no case of aloxone being used in food in China, but in recent years, the National Health Commission has repeatedly accepted the application for new food raw materials of D-aloxone, indicating that aloxone is recognized and gradually legalized in China.
Test item | Test method | Limit of quantitation | Can undertake sample matrix |
Allulose | Laboratory methods, T/CBFIA 05003-2023 D-aloxulose | Aloxone raw materials, dairy products, bakery products, beverages, jelly, candy, etc |